Matched case control study
case-control study so that the controls are similar to the cases with regard to certain key characteristics—such as age, sex, and race Matching can be performed at an individual or group level Individual matching (matched pairs) Group matching (frequency matching) 28 Group Matching
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In another words, if there is no bias in the study and the study factor is really the cause of the disease/outcome, then the case should have probability of being exposed to the risk factor more than those of control - It is difficult to find a matched control
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In a matched case-control study, what do I use for hypothesis testing in the descriptive statistics or the “univariate” associations? What analysis is appropriate for this matched case/control? 0 Matching and study design
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Imagine a case–control study conducted in West Africa to investigate the role of hepatitis B virus in the etiology of liver cancer in which controls were matched to cases on the basis of previous history of liver disease
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Matched case-control studies control for confounding by introducing stratification in the design phase of a study Cases are individually matched to a set of controls (1:n ratio); n can vary from 1 to the desired number of controls for each case
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Methods: This matched case-control study was conducted in Hamadan Province, the west of Iran, in 2012 enrolling neonates born between 2005 and 2011 and covered by screening program for congenital hypothyroidism
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MATCHING IN CASE CONTROL STUDIES Matching addresses issues of confounding in the DESIGN stage of a study as opposed to the analysis phase A means of providing a more efficient stratified analysis rather than a direct means of preventing confounding, by increasing precision of estimates
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In another words, if there is no bias in the study and the study factor is really the cause of the disease/outcome, then the case should have probability of being exposed to the risk factor more than those of control - It is difficult to find a matched control
Read...
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In a matched case-control study, what do I use for hypothesis testing in the descriptive statistics or the “univariate” associations? What analysis is appropriate for this matched case/control? 0 Matching and study design.
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Military dictionary matched pair study — see case control study … Nested case-control study — A nested case control study is a variation of a case cohort study in which only a subset of controls from the cohort are compared to the incident cases.
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A nested case control (NCC) study is a variation of a case-control study in which only a subset of controls from the cohort are compared to the incident cases In a case-cohort study, all incident cases in the cohort are compared to a random subset of participants who do not develop the disease.
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In another words, if there is no bias in the study and the study factor is really the cause of the disease/outcome, then the case should have probability of being exposed to the risk factor more than those of control - It is difficult to find a matched control.
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Imagine a case–control study conducted in West Africa to investigate the role of hepatitis B virus in the etiology of liver cancer in which controls were matched to cases on the basis of previous history of liver disease.
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In another words, if there is no bias in the study and the study factor is really the cause of the disease/outcome, then the case should have probability of being exposed to the risk factor more than those of control - It is difficult to find a matched control.
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